Now that Harriett Miers has withdrawn, the question is "Who will President Bush pick now". Many moderates and liberals have worried that if her nomination failed due to opposition from the right, Bush would nominate someone more acceptable to the extreme right. He could nominate someone who has a proven right wing track record. That was my opinion. At the time I heard about Miers' withdrawal, I was writing a comment to post here supporting Miers' confirmation because of that very possibility.
Another possibility is that Bush will decide that the far right base is not loyal to him, and ignore their wishes and appoint a more moderate person who has a solid resume for a Supreme Court nominee. The Republican senators would not have the excuse of "lack of experience" as a base for their opposition. A moderate would also draw at least some support from the Democratic senators.
We will just have to wait and see.